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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PTPRC
All Species:
8.79
Human Site:
Y453
Identified Species:
17.58
UniProt:
P08575
Number Species:
11
Phosphosite Substitution
Charge Score:
-0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P08575
NP_002829.2
1304
147254
Y453
N
L
K
P
Y
T
K
Y
V
L
S
L
H
A
Y
Chimpanzee
Pan troglodytes
XP_001141776
1304
147111
Y453
N
L
K
P
Y
T
K
Y
V
L
S
L
H
A
Y
Rhesus Macaque
Macaca mulatta
XP_001114682
793
89729
S38
I
T
R
L
I
N
S
S
T
A
E
P
V
K
E
Dog
Lupus familis
XP_547374
1251
141725
K440
R
D
L
H
F
S
R
K
S
D
N
S
V
Q
V
Cat
Felis silvestris
Mouse
Mus musculus
P06800
1291
144386
Y442
S
L
K
P
Y
K
Y
Y
E
V
S
L
L
A
Y
Rat
Rattus norvegicus
P04157
1273
143251
A442
R
V
Q
R
N
G
P
A
K
D
C
N
F
R
T
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001505908
547
62553
Chicken
Gallus gallus
NP_989748
1237
139302
T448
Q
K
V
Y
G
N
E
T
K
F
K
L
S
W
N
Frog
Xenopus laevis
NP_001089394
819
92510
P64
S
E
S
Q
T
T
A
P
V
T
T
T
K
P
P
Zebra Danio
Brachydanio rerio
XP_687562
666
75982
Tiger Blowfish
Takifugu rubipres
NP_001027788
1246
141346
F441
F
S
V
L
D
R
V
F
L
Y
R
T
E
P
G
Fruit Fly
Dros. melanogaster
P16620
1462
167441
H478
K
V
V
S
Y
L
I
H
L
L
G
N
P
M
S
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.4
27.9
69.1
N.A.
66.5
65.8
N.A.
32.5
50
28.1
27.8
38.9
25.5
N.A.
N.A.
N.A.
Protein Similarity:
100
99.2
40.9
78.9
N.A.
76.1
75.8
N.A.
37.5
64.7
41.9
36.8
55.6
42.8
N.A.
N.A.
N.A.
P-Site Identity:
100
100
0
0
N.A.
60
0
N.A.
0
6.6
13.3
0
0
13.3
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
6.6
26.6
N.A.
73.3
13.3
N.A.
0
13.3
26.6
0
13.3
33.3
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
9
9
0
9
0
0
0
25
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
9
0
0
0
0
% C
% Asp:
0
9
0
0
9
0
0
0
0
17
0
0
0
0
0
% D
% Glu:
0
9
0
0
0
0
9
0
9
0
9
0
9
0
9
% E
% Phe:
9
0
0
0
9
0
0
9
0
9
0
0
9
0
0
% F
% Gly:
0
0
0
0
9
9
0
0
0
0
9
0
0
0
9
% G
% His:
0
0
0
9
0
0
0
9
0
0
0
0
17
0
0
% H
% Ile:
9
0
0
0
9
0
9
0
0
0
0
0
0
0
0
% I
% Lys:
9
9
25
0
0
9
17
9
17
0
9
0
9
9
0
% K
% Leu:
0
25
9
17
0
9
0
0
17
25
0
34
9
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
9
0
% M
% Asn:
17
0
0
0
9
17
0
0
0
0
9
17
0
0
9
% N
% Pro:
0
0
0
25
0
0
9
9
0
0
0
9
9
17
9
% P
% Gln:
9
0
9
9
0
0
0
0
0
0
0
0
0
9
0
% Q
% Arg:
17
0
9
9
0
9
9
0
0
0
9
0
0
9
0
% R
% Ser:
17
9
9
9
0
9
9
9
9
0
25
9
9
0
9
% S
% Thr:
0
9
0
0
9
25
0
9
9
9
9
17
0
0
9
% T
% Val:
0
17
25
0
0
0
9
0
25
9
0
0
17
0
9
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
9
0
% W
% Tyr:
0
0
0
9
34
0
9
25
0
9
0
0
0
0
25
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _